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Retatrutide has not been compared head-to-head with earlier GLP-1 medications in any clinical trials, although there is an ongoing trial called TRIUMPH-5, which is comparing it with tirzepatide

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doi: 10.3389/fphar.2024.1410479 Received 01 April 2024 Accepted 21 May 2024 Published 11 June 2024 Volume 15 - 2024 Edited by Lin Zhu, Vanderbilt University Medical Center, United States Reviewed by Feng Liu, Soochow University Medical College, China Kenneth Maiese, National Institutes of Health (NIH), United States Updates Copyright 2024 Sun, Zhu, Li, Mei, Li and Li