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Description
Becoming limitless
P-gp, encoded by the ABCB1 gene, is the most studied transmembrane transporter in the ABC transporter family
The 75 mg dosage thus represents a valid alternative to the usually recommended 50 mg starting dose, as well as a potential solution to rescue patients who would otherwise discontinue treatment because of either lower efficacy (using a lower dose) or more frequent side effects (using a higher dose)
G., Kumar, S., Hitman, G
Circulation 104 , 18941898 (2001)
