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Diabetic rats received insulin (1 IU sc/day), metformin (10 mg/kg/day p.o.) alone, l-carnitine (75 mg/kg/day, i.p.) alone, and a combination of l-carnitine (75 mg/kg/day)+metformin (10 mg/kg/day) daily for 14 days

Adequate levels of GSH are essential for the optimal functioning of the immune system in general and T cell activation and differentiation in particular

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Results The constructed AD-related pathway-gene network encompassed three perspectives: (i) Most Studied Pathways (21 pathways with 5325 genes), (ii) Gene-Associated Pathways (26 pathways with 2557 genes), and (iii) Popular Pathways (24 pathways with 3435 genes)