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[DOI] [PubMed] [Google Scholar] 284.Graybeal AJ, Kreutzer A, Rack P, et al
doi: 10.1093/ajcn/53.6.1466
doi: 10.1038/nature05485 10 RenGKimJYSmasCM
Their accumulation in adipose tissue leads to insulin resistance and inflammation, both of which contribute to the development of atherosclerosis as insulin resistance progresses, the adipose tissue secretes higher levels of adipokines, signaling molecules that promote inflammation and increase the risk of atherosclerosis
