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Neurological symptoms often develop gradually and may include: Paraesthesia : tingling or 'pins and needles' sensations, typically starting in the feet and hands Numbness : reduced sensation in the extremities, which may affect balance and coordination Burning pain : particularly in the feet, often worse at night Weakness : muscle weakness and difficulty walking Balance problems : unsteady gait and increased fall risk due to proprioceptive impairment Cognitive changes : memory problems, confusion, difficulty concentrating, and mood disturbances Haematological signs may accompany neurological symptoms and include fatigue, weakness, pallor, and shortness of breath due to megaloblastic anaemia

In addition, B12 shots play a crucial role in supporting the functioning of the nervous system

The relative band intensities were normalized to the loading control (-actin)

Search interest in TB-500 has grown over 800 percent in the past year, and the interest reflects something real

These figures, however, probably underestimate the actual prevalence of PSC, as the disease can occur in patients with normal serum levels of alkaline phosphatase, and 2030% of patients with PSC have no associated IBD