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Annals of the new York Academy of Sciences, 1184, 173187
Clinical trials like the NIH-sponsored TACT trial revealed modest benefits, including decreased cardiovascular events
In addition to dipeptide linkers, the tetrapeptide Gly-Gly-Phe-Gly has also been successfully employed in ADCs, exhibiting enhanced stability in circulation compared to dipeptides [140, 141]
This experiment was repeated two more times and similar results were obtained (Supplemental Figure S3)
Now picture the same man, same drinks, same time frame but he spent the afternoon in the heat without drinking water and is mildly dehydrated
