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Sallum JMF, Kaur VP, Shaikh J, Banhazi J, Spera C, Aouadj C, Viriato D, Fischer MD

Although in most of the reviewed studies riboflavin status was found to be inversely related to lipid peroxidation, only in some of these studies, this relationship could be attributed to the role of riboflavin in the activities of glutathione reductase and related antioxidant enzymes

Data availability All data are available in the main manuscript and supplementary material and all relevant data is available from the authors

When Coffee Enemas May Be Safer People who choose to try coffee enemas can reduce risk by: Using lukewarm, properly brewed coffee Limiting frequency (not daily or long-term without guidance) Staying well-hydrated before and after Using clean, well-sterilized equipment Important Note: If you have any existing health concerns, or if youre unsure whether coffee enemas are appropriate for you, its best to speak with a qualified healthcare provider or trained practitioner