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Angew Chem Int Ed 45:45624589

Methods: Dogs received immunosuppressive chemotherapy of 0.5 mg/kg pentostatin for 3 days and, on the 3rd day, 300 mg/m2 cyclophosphamide along with supportive IV fluid and concomitant medications

COMPOSITION Glutathione Cindella Thioctic Acid Vitamin C INDICATION Nourishes and firming the skin Whiten skin and lighten scar Produce collagen and enhance the elasticity of skin Moisture and hydrate skin Firm smooth and soften skin Reduces pigmentation caused from exposure to sunlight Smooth fine lines and wrinkles Suppresses the formation of acne blemish pimples Minimize pores and improves skin complexion Remove excess free radicals that will cause abnormal function of brains and organs Prevent formation aging Anti wrinkles free DOSAGE AND ADMINISTRATION Initial dose: 1-2 injections in the vein (IV) or intramuscular (IM) every week for up to a month

Bao 25 , 4447 (2019)

In vivo analysis revealed that a high-Met diet can induce HHcy and can affect epigenetic processes, mainly increased global methylation (5-mC) and DNA methyltransferase-1 (DNMT1) expression