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B., Nuevo-Tapioles, C

doi: 10.1111/ejn.14913, 84 HockleyA.ShoreS

Compared to oral and intravenous administration, pulmonary drug delivery has the advantages of local lung targeting, high local drug concentration and rapid onset of action, low systemic distribution and toxicity, avoided degradation in the gastrointestinal tract and hepatic firstpass metabolism, and good patient compliance without using needles [4, 5]

Inhaled pharmacologic therapy is a cornerstone treatment for patients with COPD [104]

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