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The IEB has two main roles: it is both responsible for nutrient absorption and serves as the first line of defense against external pathogens

doi: 10.1016/j.ecoenv.2023.115587 12 JiangLWuQBaoSFanGYangZZhouPet al

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In general, there is an age-related increase of 5hmC levels in the brain, pointing towards a role for 5hmc in the development of AD [136, 149, 150]
