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If you want to run longer, that's a personal choice, not a medical risk at standard doses

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Reference: Dimet-Wiley AL, Latham CM, Brightwell CR, Neelakantan H, Keeble AR, Thomas NT, Noehren H, Fry CS, Watowich SJ (2024)

Intestinal epithelial NAD+ biosynthesis regulates GLP-1 production and postprandial glucose metabolism in mice

SLC1A5 might not be an appropriate target for suppressing glutamine uptake by cancer cells because it is not the only plasma membrane glutamine transporter, and its function would therefore be compensated by other redundant glutamine transporters such as SLC38A1 and SLC38A2
