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Description
Our model also accounts for the efficacy of commonly-used treatments of CVS, including mitochondrial-targeted therapies, propranolol (beta blockade interferes with catecholamine-induced release of calcium via the RYR2 calcium channel (101), and amitriptyline (used for peripheral neuropathy)

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As the glucose is excreted there is a concomitant loss of water to maintain normal osmolarity of the urine
3 Dermatoscopic examination of a nevus reveals a brown coloration of the background and regular parallel longitudinal brown lines