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For questions about individual nutrient interactions, refer to the individual product pages or consult your healthcare provider

PMID 19178874

Choline and L-carnitine that are not absorbed in the small intestine are metabolized by the gut flora into trimethylamine (TMA) in the colon and then oxidized to TMAO in the liver by Flavin-containing monooxygenase 3 (FMO3) ( Anaerococcus hydrogenalis , Clostridium asparagiforme , Clostridium hathewayi (Romano et al., 2015)

meanwhile, in the adrenal cortex, Ang II stimulated the secretion of aldosterone, thereby increasing the absorption of water and sodium in collecting duct principal cells (120)

L-carnitine supplementation is associated with lower blood pressure, total cholesterol, LDL (bad) cholesterol, and triglycerides, and when these markers are elevated, the risk of heart disease and heart failure increases, Zenker says