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This heterogeneity is partly genetic: mouse strains with polymorphisms in the Slc6a4 gene (encoding the 5-HT transporter) exhibit divergent responses to ethanol, with short-allele carriers showing heightened vulnerability to depression-like phenotypes

However, too much protein can lead to reduced carbohydrate intake with consequent weight loss, and such diets can cause harm to kidney function due to increased urinary excretion of amino acids, which can elevate acid load and precipitate metabolic acidosis, especially in patients with poor kidney function

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Boink MA, Roffel S, Nazmi K et al (2016) The influence of chronic wound extracts on inflammatory cytokine and histatin stability

PMID: 8877962 Heary, R.F., Albert, T.J., Ludwig, S.C., Vaccaro A.R.., Wolansky, L.J., Leddy, T.P., Schmidt, R.R.: Surgical Anatomy of the Vertebral Arteries