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Description
M2 macrophages possess a weak antigen-presenting ability, and secrete anti-inflammatory cytokines such as IL-10 or TGF-, and down-regulate the immune response [88,89,90].Tumor-associated macrophages (TAMs) have been shown to be functionally plastic as a special type of macrophage, which are often described as M2-like population, but there is also evidence for the existence of M1-like population [91,92,93].In fact, in the early phase of tumor establishment, TAMs display an inflammatory phenotype, but an immunosuppressive phenotype is present at the later stages of tumor progression [94]

Nature 2018, 561 (7721), 6369

When the body does not produce enough glutathione, it can lead to many health problems

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[DOI] [PubMed] [Google Scholar] 31.Xu L, Li Y, Dai Y, Peng J
