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Description
Prostaglandin E2 promotes features of replicative senescence in chronically activated human CD8 + T cells
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Conflict of interest The authors declare that there are no conflicts of interest
O.Brown-BorgH
277,278,279 When dysfunctional mitochondria cannot be cleared in time by mitophagy, damaged mitochondria accumulate, which results in insufficient energy supply as well as overproduced ROS, thereby triggering intense oxidative stress and cellular damage
