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Although this carrier design utilizes simple materials, its hypoxia responsiveness may be constrained by tumor heterogeneity

Such depletion can be due to reduction of GSH due to excessive NAPQI exposure and/or to GSH depletion associated with elevated dopamine secondary to dopamine -hydroxylase inhibition by phenolic Clostridia metabolites

doi: 10.1016/S1044-0305(02)00347-1

Buerger, S