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Accumulation of caveolin in the endoplasmic reticulum redirects the protein to lipid storage droplets

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The estimated net effect sizes were medium (defined as Cohens d of 0.50.79) for the Average of all scores, Overall, tantrums/meltdowns, cognition/thinking, and receptive language, and small (defined as 0.20.49) for play/leisure skills, sleep, eye contact, stools/GI problems, expressive language/speech, and sociability)

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Body-weight scaling is not straightforward: allometric differences in metabolism between a 2 kg rodent model and a 40 kg dog mean a simple g/kg extrapolation may not translate