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More recently, tofersen (QALSODY ), an antisense oligonucleotide targeting mutant SOD1 , has shown potential in reducing NfL levels and slowing functional decline, though concerns remain regarding inflammatory side effects and the failure of initial phase III trials [7678]
4a, b) and morphometric analysis by EM (Supplementary Fig
Upon internalization into tumor cells, TEP-FFG-CRApY transforms from nanoparticles to nanofibers in response to alkaline phosphatase (ALP) activity, facilitating lysosomal membrane permeabilization (LMP)
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Insights from myalgic encephalomyelitis/chronic fatigue syndrome may help unravel the pathogenesis of post-acute COVID-19 syndrome
