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[DOI] [PMC free article] [PubMed] [Google Scholar] 82.Pennypacker S.D., Romero-Sandoval E.A
Thnh phn glutathione chit xut t nm men kh gip y li s hnh thnh ca cc melanin hc t v nhng tc ng ca gc t do nh hng n sc khe ln da

Methotrexate, an antifolate drug used in cancer therapy, is a known inhibitor of DHFR, the enzyme that catalyzes the conversion of DHF into THF, which is required for the de novo synthesis of nucleotides for both DNA and RNA
UV exposure is the known reason for skin damage in 80% of cases

Kumar P, Liu C, Hsu JW, Chacko S, Minard C, Jahoor F, Sekhar RV
