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[DOI] [PMC free article] [PubMed] [Google Scholar] 82.Pennypacker S.D., Romero-Sandoval E.A

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Thnh phn glutathione chit xut t nm men kh gip y li s hnh thnh ca cc melanin hc t v nhng tc ng ca gc t do nh hng n sc khe ln da

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Methotrexate, an antifolate drug used in cancer therapy, is a known inhibitor of DHFR, the enzyme that catalyzes the conversion of DHF into THF, which is required for the de novo synthesis of nucleotides for both DNA and RNA

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UV exposure is the known reason for skin damage in 80% of cases

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Kumar P, Liu C, Hsu JW, Chacko S, Minard C, Jahoor F, Sekhar RV

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