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At therapeutic IV doses (often 2550 g in oncology and critical-care research), studies report improvements in inflammation markers, oxidative stress, and quality of life in advanced cancer and sepsis, although evidence is strongest for adjunctive rather than standalone use

TXNRD1 is one of the most investigated selenoproteins and regarded as one of the major antioxidant enzymes and redox regulators in mammalian cells

Stimulation of glutathione synthesis in iron-loaded mice