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Another interesting class of hypoglycemic drugs with positive kidney outcomes are the SGLT2 inhibitors (SGLT2i) which inhibit glucose and sodium reabsorption in the PT (Perkovic et al., 2019) independently of glycemic control (Williams et al., 2020)
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These findings have been confirmed in primates supplied daily by cca 19 mg/kg for 10 days (Horvath et al
Biomolecules & therapeutics, 33(1), 117128
