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For example, berberine and palmatine have been reported can exert various pharmacological activities, such as anti-inflammatory, chondroprotective, and neuroprotective properties (Singh et al., 2019

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"Gab1 phosphorylation: a novel mechanism for negative regulation of HGF receptor signaling"

In rats, IL-1 83 and TNF- 84 mRNAs show diurnal variations in different brain areas, with the highest concentrations recorded during increased sleep propensity and peaks occurring at time of sleep period onset in rats and mice 85

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