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Wu et al., 2018)

In that sense, estrogen positively regulates the expression of proteins related to mitochondrial biogenesis, such as the nuclear respiratory factor-1 (NRF-1) and the peroxisome proliferator-activated receptor-gamma coactivator 1 (PGC-1) (Kemper et al., 2013

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Keywords: Metabolic syndrome, Mitochondria, Oxidative stress, Reactive oxygen species, Mitochondria-targeted antioxidants, Cardiovascular disease, Pre-diabetes, Type-2-diabetes, Obesity Graphical Abstract 1