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(ref) Chang CH, Tsai WC, Hsu YH, Pang JH

High prevalence of diabetes mellitus in patients with chronic hepatitis C

In a letrozole-induced PCOS mouse model, 160 mg/kg/day NAC for 12 days significantly ameliorated estrous cycle irregularities and ovarian morphology, reduced serum concentrations of LH, the LH/FSH ratio, and T, improved glucose clearance and insulin sensitivity, decreased ROS levels in oocytes and enhanced mitochondrial membrane potential (185)

The specific mechanism that supports this process is still not fully determined

[DOI] [PMC free article] [PubMed] [Google Scholar] 84.Genazzani AD, Despini G, Czyzyk A, Podfigurna A, Simoncini T, Meczekalski B