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The activation of macrophages and lymphocytes which leads to a coordinated cytokine response is a hallmark of chronic inflammation (Germolec et al

Coordinative metabolism of glutamine carbon and nitrogen in proliferating cancer cells under hypoxia

Upon activation, the ratio of glucose influx to astrocyte versus neuron increases, consistent with the literature (87, 88)

All animal procedures conducted within this study were conducted in accordance with FELASA guidelines and were approved by the responsible authority (Landesamt fr Gesundheit und Soziales Berlin, LaGeSo) under license numbers ZH120, G0346/13, and G0176/19

SARS-CoV-2 infection requires a high basal energy expenditure for immune activation, hyper-inflammation (cytokine storm), anorexia followed by muscle loss, weakness, and fatigue 643
