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Exposure to triggers such as free radicals induces the translocation of NRF2 into the nucleus, where it promotes the upregulation of antioxidant proteins and plays a defensive role against oxidative damage [210]

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So the stress response pathway in this case is, uh, norepinephrine is elevated

Studies report levels of approximately 200 ng/mL in a 20-year-old individual, compared to about 80 ng/mL at age 60

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