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Our integrated omics analysis supports this receptor synergy by showing consistent downregulation of metabolic intermediates of fatty acid oxidation as well as pro-inflammatory and pro-fibrotic metabolites, confirming a unified pharmacodynamic effect across molecular and metabolic layers

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Herbs and dietary supplements in the prevention and treatment of cardiovascular disease

Figure 3 The VPC plots are shown in Figure 4, and most observed data were included in the 95% prediction intervals produced by simulation data, which shows the predictive power of the final models