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Clinical significance of the SLC33A1 encoded transporter is evident from the fact that mutation in the gene are associated with a lethal disorder identified as Huppke-Brendel syndrome (HPBDS)

D2 and D4 dopamine receptor polymorphisms and personality

This is proceeded by peptide bond formation between -Glu-Cys and the amino acid glycine which results in a reduced form of glutathione, known as GSH (Pophaly et al
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Amyloid-beta pathology is attenuated by tauroursodeoxycholic acid treatment in APP/PS1 mice after disease onset
