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Mechanistically, ox-LDL induces lipid peroxidation by inhibiting the SREBP-1/SCD1/FADS2-mediated lipid biosynthesis pathway, leading to endothelial damage and ultimately inducing ferroptosis ( 3.3 Ferroptosis and the inflammatory response The discovery of ferroptosis may explain iron accumulation's biological effects

Free Radic Biol Med 48:16261635 Moghaddam AZ, Hamzekolaei MM, Khajali F, Hassanpour H (2017) Role of selenium from different sources in prevention of pulmonary arterial hypertension syndrome in broiler chickens

Supporting these findings, a recent PET (positron emission tomography) imaging study by (Kato et al., 2023) demonstrated a significant reduction in Complex I availability in the anterior cingulate cortex of ASD individuals, reinforcing the hypothesis that compromised mitochondrial respiration plays a key role in ASD pathophysiology

Prohibited Uses: This product is not to be used as an active pharmaceutical ingredient (API) in compounding or manufacturing drugs for human or veterinary use