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The primary reaction catalyzed by GPx is: In this reaction include GSH represents reduced monomeric glutathione and GS-SG denotes glutathione disulfide

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These microclots, which are resistant to fibrinolysis, may trigger oxidative stress and the secretion of proinflammatory cytokines, establishing a vicious cycle that may be implicated in the plethora of clinical manifestations observed in LC [94,204,251]

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