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After quality control, dimensionality reduction, cell clustering, and cell markerbased annotation (Supplemental Figure 2, AC, and Supplemental Table 1), we detected 29 cell clusters, 24 of which were neuronal ( Syt1 enriched) and further categorized into glutamatergic (expressing Slc17a7 and Slc17a6 ) and GABAergic (expressing Gad1 and Gad2 ) subtypes (Figure 1, A and B, and Supplemental Figure 2C)
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In particular, l-theanine was identified as a competitive inhibitor of the cannabinoid receptor 1 (CB1)
pH 5.5 and tested for minimal irritation
