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doi: 10.1007/s00726-016-2254-8

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identified a comparable efficacy between ozone therapy and hyaluronic acid injections for knee OA pain alleviation and functional improvement [8]

Total RNA was purified using RNeasy Mini Kit (QIAGEN, 74106)

This microbial consortium demonstrates substantial -diversity (intra-individual species richness) and functional redundancy, enabling robust ecosystem stability that facilitates immune tolerance, epithelial barrier maintenance, and metabolic homeostasis through mechanisms including short-chain fatty acid (SCFA) biosynthesis (notably butyrate) and essential vitamin production (Liu et al., 2024