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Urinary excretion of carnitne in burned patients

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doi: 10.1016/j.bbamcr.2016.01.023 12 PlacidiMEmidioGDVirmaniAD'AlfonsoAArtinPGD'AlessandroAMet al

The therapeutic effects of these compounds in animal models and in vitro studies either in delaying motor symptoms, protecting against motor neuron loss and/or improving survival suggest that further studies should be performed to characterize abnormalities in energy metabolism in ALS and explore potential metabolic therapies

It also highlights the role of the peripheral nervous system in this disease