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In a cervical cancer cell line (HeLa), the compound reduced cell proliferation in a concentration- and time-dependent way and lowered expression of phospho-Akt and SIRT1, two proteins tied to tumor progression, while a non-cancer reference cell line was less affected
[DOI] [PMC free article] [PubMed] [Google Scholar] 54.Hasnain SZ, Tauro S, Das I, Tong H, Chen AC, Jeffery PL, et al
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There is no need to reduce the particle size of freely water soluble drugs, e.g
