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Most of the product licences, or marketing authorities as they are called in the UK, for hydroxocobalamin date from the 1990s when the requirement for evidence was different than it is now
The effect of dietary approaches to stop hypertension (DASH) diet on attention-deficit hyperactivity disorder (ADHD) symptoms: A randomized controlled clinical trial

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Similarly, prolactin elevation from GHRP-6 at higher doses can suppress libido, cause gynecomastia in predisposed individuals, and disrupt reproductive hormones

10.1016/j.cjca.2020.02.081 63