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However, efficient and targeted intra-articular gene delivery remains a considerable technical challenge, primarily due to the dense extracellular matrix (ECM) of cartilage, rapid clearance of joint fluid, and limited cellular uptake

The Nano-Scale Shield The Molecular Chemistry of Amphiphilic Phospholipid Bilayers Phospholipid molecules possess dual chemical properties: a hydrophilic (water-loving) head group and hydrophobic (fat-loving) tails

Its primary mechanism of action involves promoting the polymerization of tubulin, stabilizing microtubule structures, thereby preventing the normal depolymerization of microtubules during cell division, leading to cell cycle arrest at mitosis, and ultimately inducing apoptosis (Zhu and Chen, 2019)

however, the diagnosis or risk of glaucoma should be definitive before starting or changing glaucoma treatment

H., et al., Mutant KRAS is a Druggable Target for Pancreatic Cancer, Proceedings of the National Academy of Sciences of the United States of America 110, no