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Additionally, the follow-up duration was generally 30,000 participants collectively 38,39,40

Cyanocobalamin injection is commonly used for vitamin B12 deficiency related to pernicious anemia, dietary deficiency, gastrointestinal conditions, or surgeries that reduce absorption

In almost all cases, bright yellow urine after taking B vitamins is completely harmless

Trial registration The Institute of Regenerative and Cellular Medicine IRB approval number: IRCM-2021304

Glycemic category (normoglycemia, prediabetes or type 2 diabetes) was determined by investigators on the basis of available information (for example, medical records, concomitant medication, and blood glucose variables) and in accordance with American Diabetes Association criteria 30 , which for prediabetes includes fasting plasma glucose levels of 100 mg dl 1 (5.6 mmol l 1 ) to 125 mg dl 1 (6.9 mmol l 1 ) or HbA 1c levels of 5.76.4% (3947 mmol l 1 ), and for type 2 diabetes includes fasting plasma glucose levels of 126 mg dl 1 (7.0 mmol l 1 ) or HbA 1c levels 6.5% (48 mmol l 1 )