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A significant decrease in adenosine triphosphate (ATP) levels as a result of age and elevated IOP in the optic nerve, as well as a correlation between the rate of axonal dysfunction and the depletion of energy substrates as a result of oxygenglucose deprivation, further implicate metabolism in glaucoma pathogenesis (Baltan et al., 2010)

Shokolenko et al., 2014

Science 357:10471052

J Clin Invest 2015;125:2293306.ArticlePubMedPMC 159

Biosynthesis of the protein encoded by the c-met proto-oncogene