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MSNs functionalized with antiviral drugs (e.g., oseltamivir, acyclovir) enhance the uptake of antiviral drugs into the mucosal cells and increase the stability of the drugs [274]
Some forms of damage to biochemical structures occur from the reaction of chemically reactive (usually) small molecules with the nucleophilic centers of proteins and of DNA, that generate stable addition products, commonly referred to as adducts [83]
1A, E, F)
Possible strategies to cross the bloodbrain barrier
