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Together, our results indicated that the shortened lifespan of mog-3(-) worms require the same genetic components that also mediate MID, supporting shared molecular mechanisms that drive lifespan reduction in MOG worms and during MID

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At the initial baseline visit, serial venous sampling performed after oral d 3 -l-carnitine challenge revealed rapid increases in plasma concentrations of d 3 -l-carnitine, and subsequent increases in d 3 -BB and d 3 -TMAO following a lag phase (Figure 1, AC, filled circles)