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Experiments using opioid and dopamine antagonist drug challenges suggest that specific changes in dopaminergic pathways lead to the development of RLS

Because the body cannot naturally produce B12, it must be obtained from diet or supplementation, unlike many other vitamins

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It may offer neuroprotective, angiogenic, wound healing and tissue growth propertiesand all of these benefits have been noted in preclinical studies, although human research is severely lacking
