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Description
Feb 2010;133(2):136-43

Routes of administration include intraventricular, intracarotid, intravenous and intraperitoneal injection each producing different effective central exposures of an unstable peptide

So, if you want to be really professional, dont choose, but combine : You can use a serum that contains both (e.g., Numbuzin No.5 or APLB products)
Yehuda, A

Specifically, mild intermittent hypoxia exposure modified the gut microbiota composition in overweight/obese males, enhancing certain butyrate-producing anaerobic taxa