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Abstract The RNA-binding protein FUS/TLS, mutation in which is causative of the fatal motor neuron disease amyotrophic lateral sclerosis (ALS), is demonstrated to directly bind to the U1-snRNP and SMN complexes

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Zhang L, Pitcher LE, Yousefzadeh MJ, Niedernhofer LJ, Robbins PD, Zhu Y (2022) Cellular senescence: a key therapeutic target in aging and diseases

The canyon has points between 3,600 and 4,800 meters (11,811 15,748 ft) above sea level
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