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The next generation of drugs just degrades them

Cystine, once transported into the -cells by SLC7A11, is reduced to cysteine

This review emphasizes UPS as a promising therapeutic modality for the treatment of kidney disease

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However, the biological effectsincreased synaptic density, elevated expression of synaptogenic proteins like synaptophysin and PSD-95, and enhanced dendritic spine formationpersist for 7-14 days after administration
