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Recent evidence by Bao et al

Since L-dopa is converted to dopamine in the CNS and the peri phery, peripheral conversion and systemic effects can be reduced by combining L-dopa with carbi dopa (a peripheral decarboxylation inhibitor), which does not cross the bloodbrain barrier

doi: 10.1006/abio.1993.1529 53 MhamdiA.HagerJ.ChaouchS.QuevalG.HanY.TaconnatL.et al

Pejman Sani, M

Dallman, M
