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Similar to NNMT overexpression, MNA-treated hepatocytes show a dose-dependent increase in glucose production, Sirt1 protein expression, G6pc mRNA expression, and Pck1 mRNA expression compared to controls and these changes caused by MNA treatment can be abolished by Sirt1 knockdown [14]
Vitamin B12 injections may be recommended for our patients who have difficulty absorbing this essential nutrient through diet or oral supplements
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Data availability The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request
