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Improvement rate slows as scars reach their maximum response potential

In this example and in type 1 diabetes, it has been discussed whether the normalization of glucose metabolism following rhIGF-I therapy is most importantly associated with insulin-like effects of IGF-I on glucose uptake in muscle or suppression of GH hypersecretion

While hormone optimization has become widely recognized, another important factor is the decline of specific regenerative peptides in the body

J Periodontol 66(6):429437
