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By targeting distinct but interconnected pathways, this synergy could more effectively counteract the oxidative stress and inflammatory cascades that fuel colorectal tumorigenesis

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In addition to its primary role as growth factor, human growth hormone (hGH) can also participate in cell survival, as already documented by its protective effect on human monocytes or human promyelocytic leukaemia U937 cells exposed to a Fas-mediated cell death signal

Univariate and multivariate analyses were performed to assess its efficacy in predicting PFS and overall survival(OS)