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They really can really trick you into thinking that a given compound is doing something when in fact, it's not doing anything different than would an injection of saline, of salt water

Hooshmand B et al., Neurology 2010 B12 status and brain volume in elderly

There is no gold standard test that gives a clear, unequivocal answer to the question does this person have a vitamin B12 deficiency, yes or no

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